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Uppsalalaan 8 2 day event 19 - 20 Apr. Jop Kind, Junior Group Leader at the Hubrecht Institute. Jop Kind received his PhD from the Radboud University Nijmegen in 2008 for his work on chromatin and gene expression in the research group of Asifa Akhtar at EMBL Heidelberg. This type of DNA damage can have an endogenous cause, but it can also be caused by external influences, such as high dosages of chemotherapy in cancer. By Jop Kind, Hubrecht Institute. Save the date for our Annual Conference! Geert Kops Group. Dive into the research topics where Jop Kind is active. Save the date for our Annual Conference! Jop Kind. Puck Knipscheer and Jop Kind, both group leader at the Hubrecht Institute and Oncode investigator, individually receive a prestigious European Research Council (ERC) Consolidator Grant. Jobs. Login as Dr. J. About the Hubrecht Institute Jop Kind is group leader at the Hubrecht Institute and Oncode Investigator. Jop Kind, group leader at the Hubrecht Institute, has been awarded the John Kendrew award. 12:35. In addition, scDam&T allows determining cellular identity of cells in complex tissues -such as embryos or tumors- based on transcriptomics, in direct relation to their epigenetic regulatory landscapes (DamID). 2 day event 04 - 05 Nov. Oncode - CGC Annual Conference: Basic biology meets Cancer research. We are interested in how cells acquire new identities and traits in lineage specification events in mice and in cancer. Credit: Jop Kind, copyright Hubrecht Institute. EMBL alumnus Jop Kind’s research focuses on the role of DNA organisation in genome stability, cell development and disease. jop kind Hubrecht Institute Verified email at hubrecht.eu. degree at EMBL Heidelberg and conducted her PhD research on the topic of Chromatin and Biomedical Genetics at Hubrecht Institute as a Marie-Curie fellow. She and others previously discovered that the Fanconi anemia (FA) pathway plays a crucial role in repairing ICLs. Accurate repair of DNA damage is critical for the maintenance of genomic integrity. Technology development Here For You During COVID-19 NEW! Over 17 years of experience in Molecular Biology, Yuva completed her MSc. The grant enables them to develop their own innovative line of research and set up their own research group. 7 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands. Hubrecht Institute, Developmental Biology and Stem Cell Research | 6,134 followers on LinkedIn. Save the date! Over 17 years of experience in Molecular Biology, Yuva completed her MSc. Mechanisms underlying cell-fate choice in early embryogenesis Online event. Former EMBL Genome Biology PhD student, Jop Kind, has been selected as this year’s John Kendrew Young Scientist Award winner for pioneering postdoctoral work in establishing novel technologies to map chromatin domains in single cells. 23. Best Cities for Jobs 2020 NEW! That way, we hope to better understand the relationship between epigenetics and the emergence of new cell types”, says Kind. Genomic regions contacting the NL are lamina associated domains (LADs), which contain thousands of genes that are lowl … Biomedical genomics; This is particularly difficult to study because DSBs occur randomly in the genome, thus every single cell harbors a different DSB-landscape. Sort by citations Sort by year Sort by title. As a postdoctoral fellow in the lab of Bas van Steensel at the NKI, Jop developed novel techniques to visualize and profile single-cell spatial genome organization. Sara is now working as a computational biologist in the lab of Jop Kind at the Hubrecht Institute (Netherlands). hubrecht.eu. torres-padilla@helmholtz-muenchen.de. Furthermore, as we consider technology development a core business of the group, we are continuously exploring ways to obtain richer single-cell datasets. A large proportion of the metazoan genome is spatially segregated at the nuclear periphery through genomic contacts with the nuclear lamina, a thin meshwork of lamin filaments that lines the inner-nuclear membrane. Wouter de Laat Group. That knowledge underlines the link between alcohol consumption and cancer. Jop Kind, Junior Group Leader at the Hubrecht Institute. Chromatin cartographer EMBL alumnus Jop Kind, this year’s John Kendrew Award winner, reflects on … Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands. The European Research Council (ERC) awards grants to individual scientists of all nationalities and ages who perform groundbreaking research. Oncode Investigator at Hubrecht Institute My Research Jop Kind received his PhD from the Radboud University Nijmegen in 2008 for his work on chromatin and gene expression in the research group of Asifa Akhtar at EMBL Heidelberg. Despite extensive research into the molecular pathways that sense and repair DNA double-strand breaks (DSBs), comparatively little is known about management of breaks within different genomic and chromatin contexts. Royal Netherlands Academy of Arts & Sciences (KNAW) Phone +31 (0)30 212 1800; Email communication@hubrecht.eu; Website http://www.hubrecht.eu/ PhD. To study DSB-repair in single cells, we have adapted scDam&T to generate maps of DSB-repair sites in single cells. Electronic address: j.kind@hubrecht.eu. Spatiotemporal regulation of genomic function; Hubrecht Institute. The following articles are merged in Scholar. Projects 1. jop kind. Contact. Puck Knipscheer Group. Job Corps is the largest Free residential education and job training program for young adults ages 16–24.. We connect you with the skills and education you need to get the career you want! Biomedical genomics; Hubrecht Institute. The researchers are each given two million euros to strengthen their research groups and continue their innovative research in the next 5 years. To be announced. Read more | 5 November . An important contributor to the regulation of gene expression is the spatial positioning of genes within the 3-dimensional space of the nucleus. Verified email at hubrecht.eu. Puck Knipscheer Group. 13:35. He will zoom in on single-cell epigenomics and multi-omics. Molecular biologist dr. Jop Kind (1978) joined the Van Steensel lab as a postdoc after a highly successful PhD at the EMBL. Read more | 11 November . Since October 2014 he is Junior Group Leader at the Hubrecht Institute. Maria-Elena Torres-Padilla is group leader and director of the Institute of Epigenetics and Stem Cells (IES), Helmholtz Center Munich and professor of Stem cell biology at the Ludwig-Maximilians University. The John Kendrew Young Scientist Award (JKA) was launched in 2007 as an initiative from the EMBL Pensioner’s Association to honour EMBL’s first Director General, Sir John Kendrew (1975-1982), and to support scientists in the early stages of their career. The ERC-starting grants are awarded to support up-and-coming research leaders who have recently established their own research team in Europe. Jop Kind leads a Developmental Epigenomics group at Hubrecht Institute, Netherlands. 2 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, The Netherlands. Fingerprint. Jop Kind obtained his PhD from the Radboud University in Nijmegen for his work on dosage compensation in the lab of Asifa Akhtar at the EMBL Heidelberg. Researchers of the Hubrecht Institute (KNAW) in Utrecht, The Netherlands, and the MRC Laboratory of Molecular Biology in Cambridge, United Kingdom, have discovered a new way in which the human body repairs DNA damage caused by a degradation product of alcohol. hubrecht.eu. A. Lochs †, Samy Kefalopoulou † and Jop Kind * Oncode Institute, Hubrecht Institute–KNAW and University Medical Center Utrecht, 3584 Utrecht, KIT, Royal Tropical Institute. Sort. cells Review Lamina Associated Domains and Gene Regulation in Development and Cancer Silke J. Hubrecht Institute launches new website! This is particularly difficult to study because DSBs occur randomly in the genome, thus every single cell harbors a different DSB-landscape. Molecular biologist dr. Jop Kind (1978) joined the Van Steensel lab as a postdoc after a highly successful PhD at the EMBL. The grant allows her to expand her group with 4 researchers for the duration of 5 years. martin 1st April 2015 News Read more Hiding in plain sight j.kind@hubrecht.eu. Annual Scientific Meeting. Further, in the same cells, we also profile genome-wide chromatin states with a chromatin immunocleavage (ChIC) approach to study the relationships between DSB-repair and the local chromatin environment (Figure 3). Furthermore, they aim to develop new techniques with which they can simultaneously perform multiple measurements in a single cell. Jobs; Jobs Tips; 11 Recession-Proof Jobs; How to Get a Job; The Perfect Resume Looks Like This; How to Write A Cover Letter; 9 Attention-Grabbing Cover Letter Examples; New On Glassdoor; Best Cities for Jobs 2020; Company Reviews . The nuclear lamina (NL) is a thin meshwork of filaments that lines the inner nuclear membrane, thereby providing a platform for chromatin binding and supporting genome organization. The aim of the lab is to understand the principles governing cellular decision-making. Jop Kind lab. Reads . We employ our single-cell genomic methods to study cellular trajectories on route towards malignant metastatic identities. Contact Information Mariëlle Harlé Other Events. Royal Netherlands Academy of Arts & Sciences (KNAW), Hubrecht Institute; 2015 2020. Oncode unites science, collaboration and valorization to create impact for patients. Merged citations. Network. Currently, there are more than 70 PhD students at the Hubrecht Institute. Chromatin cartographer EMBL alumnus Jop Kind, this year’s John Kendrew Award winner, reflects on the imaginative questions that led him to the prize . Key words: Single-cell genomics, epigenetics, spatial genome organization, bioinformatics, gene-regulation, embryogenesis, tumorigenesis. Former EMBL Genome Biology PhD student, Jop Kind, has been selected as this year’s John Kendrew Young Scientist Award winner for pioneering postdoctoral work in establishing novel technologies to … 13:05. Despite extensive research into the molecular pathways that sense and repair DNA double-strand breaks (DSBs), comparatively little is known about management of breaks within different genomic and chromatin contexts. The Consolidator Grant is specifically awarded to researchers who have formed their own research group relatively recently and aim to further strengthen it further. Year; Systematic protein location mapping reveals five principal chromatin types in Drosophila cells. Hubrecht Institute. Get Funding: Convey the impact of your scientific vision. Publications 23. Erasmus University Medical Center/ UFO Biosciences, NL . Wednesday 22 July. Self-organization in embryology. Jop Kind. Biography. Kim L de Luca 1 , Jop Kind 2 ... 1 Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), University Medical Center Utrecht and Oncode Institute, Utrecht, The Netherlands. Accurate repair of DNA damage is critical for the maintenance of genomic integrity. j.kind@hubrecht.eu. Save the date! ); s.kefalopoulou@hubrecht.eu (S.K.) Molecular mechanisms and regulation of DNA repair; Hubrecht Institute. 3,331. Hubrecht Institute, NL. Jop is currently an associate professor at the Hubrecht Institute in Utrecht where his lab continues to develop new techniques to single-cell profile gene-regulation to obtain better insights into the mechanisms that govern cell fate choice in development and disease. 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